Improving Global Virologic Surveillance for Measles and Rubella

The largest annual total of cases of rubella in the United States was in 1969, when 57,686 cases were reported (58 cases per 100,000 population). If a negative result is obtained from serum collected within 72 hours after rash onset, a second serum should be collected ≥72 hours after rash onset. This test should be used to confirm every case of measles that is reported to have some other type of laboratory confirmation. Questions and answers on legal authorities for isolation and quarantine. Most transmission likely occurs several days before and after parotitis onset. residents who had traveled abroad recently.

J Infect Dis 2011;203:1517–25. If more than 72 hours but fewer than 6 days have elapsed since exposure, immune globulin may prevent or modify measles infection in susceptible individuals. These women should be vaccinated immediately after delivery and tested at least 3 months later to ensure that they have presumptive evidence of immunity to rubella and measles. Hepatitis A, B, & C are the three major viruses that cause hepatitis. To facilitate airflow direction from room to outside, exhaust fans should be installed (hybrid approach). Transmission-Based Precautions are designed for patients documented or suspected to be infected with highly transmissible or epidemiologically important pathogens for which additional precautions beyond Standard Precautions are needed to interrupt transmission in hospitals.


In: Remington JS, Klein JO, Wilson CB, et al., editors. Anyone at risk who is not fully vaccinated should receive vaccine as soon as possible. Tanya Karapurkar Bashin (CPHE), and Dr. Although case investigation forms may vary among the states, all programs collect data about a series of key variables. Natural ventilation has been proven as an effective method of removing airborne infectious agents (32, 33). When this was not available, the date of the first reported symptom (mostly fever) was used to calculate the time interval between the onset of symptoms and phlebotomy (16; G.

The original Edmonston B vaccine strain had an unacceptably high rate of fever and rash, but further attenuation led to the Edmonston-Moraten strain, which became the seed strain available in the United States [7]. National Health Service. However, there is no increased risk for congenital anomalies as has been reported in other diseases contracted during pregnancy, such as toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and human immunodeficiency virus. Community contacts were informed of their potential exposure through telephone calls, letters, television, radio, or print media and instructed to contact their physicians. Any measles virus that is isolated should be amplified by repeat passage then frozen for long-term storage and referred to a reference laboratory for further characterisation. I share his belief that CDC decision-making and analyses should be transparent.” However, Thompson went on to say that Hooker had recorded these conversations without his consent, and had posted them online without his knowledge.

Following culture, viral RNA was isolated using NucliSens easyMAG. Tasaka and Y. The Primary Health Information System (PHIS) was first established for public health stations in every township in the 1990s. Accordingly, the current vaccination strategies in these regions aim to interrupt all chains of transmission and intensify surveillance for suspected cases of measles (4, 5, 7). Parainfluenza viruses attach to the host cell by the hemagglutinin, which binds to the host cell neuraminic acid receptor, and then penetrate the cell by fusion with the cell membrane mediated by the F1 and F2 glycopeptides. Postexposure prophylaxis should be considered in unvaccinated contacts; timely tracing of contacts should be a priority.

4th ed. Discussion: The epidemiological linkages of the cases and laboratory findings suggest nosocomial transmission in Wards A and B. Measles is a highly contagious respiratory disease that generally affects young children, causing fever, a runny nose, a cough and a distinctive rash all over the body. Because many doctors currently in practice may not be familiar with measles signs and symptoms, CDC is asking for your help to raise awareness about measles among your members. has seen more cases of measles than at any time since 1996 in the last six months—and its stories like that that have caught the attention of actress Amanda Peet, among others concerned about the resurgence. Using dilution series of synthetic RNAs, the limits of detection were determined to be approximately 10 copies for each target RNA/reaction.